Title
Assistant Professor of Pediatrics
Education
AB – University of Chicago; 1991
PhD – University of Chicago; 1996
MD – University of Chicago, Pritzker; 1999
Postgraduate Training
Residency – Children’s Memorial Hospital, Chicago
Pediatric Neurology Fellowship– Children’s Memorial
Hospital, Chicago
Clinical Interests
- General child neurology
- Congential malformations (birth defects) of the brain and spinal cord
- Familial epilepsy
Research Interests
Congenital defects of the nervous system, especially neural tube defects, familial epilepsy, neurogenetics, neural stem cell biology
Our laboratory is interested in understanding the basic mechanisms underlying both normal and disordered development of the nervous system. Our approach to these issues includes investigating the genetics of human neural tube defects (NTDs) and familial epilepsies, and elucidating the biology regulating neural stem cell development. The techniques used in our laboratory include genome wide linkage analysis (GWA), association studies, comparative genomic hybridization (CGH), copy number variation (CNV) analysis, transgenic mouse production, and cell culture. As part of our studies we have collected DNA samples from over 2000 patients and family members with congenital nervous system malformations, and several large families with autosomal recessive epilepsy syndromes.
Lab Members
- Shu Wu (research assistant)
- Mark Fox (research assistant)
- Polly Ferguson (collaborator)
- John Wemmie (collaborator)
- Shan Chen (research assistant)
- Hatem El-Shanti (collaborator)
Affiliations
- Department of Neurology
- Interdisciplinary Program in Genetics (IDGP)
Model System
Human genetics, mouse genetics, cell culture
Recent Publications
Back to Department of Pediatrics
|
Division of Child Neurology
Recent Publications
Contact Information:
Office: 319-356-7726
Lab: 319-356-4855
E-mail: alexander-bassuk@uiowa.edu |
